no over-the-counter product was designed to do. it provides estrogens to help rebuild vaginal tissue and make intercourse more comfortable. premarin vaginal cream treats vaginal changes due to menopause and moderate-to-severe painful intercourse caused by these changes. don't use premarin vaginal cream if you've had unusual bleeding, breast or uterine cancer, blood clots, liver problems, stroke or heart attack, are allergic to any of its ingredients or think you're pregnant. side effects may include headache, pelvic pain, breast pain, vaginal bleeding and vaginitis. estrogen may increase your chances of getting cancer of the uterus, strokes, blood clots or dementia, so use it for the shortest time based on goals and risks. estrogen should not be used to prevent heart disease, heart attack, stroke or dementia. ask your doctor about premarin vaginal cream. and go to premarinvaginalcream.com this is worth talking about.